Features of responders to Tolvaptan in CKD patients

Features of responders to Tolvaptan in CKD patients - CKD-FORT study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000013366

Enrollment

Registered

2014-03-07

Start date

2013-12-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria are as follows: CKD 4 and 5 patients with volume overload and insufficient response to loop or other diuretic agents; older than 20 years old; being able to express clear understanding of the purpose of the study; being able to complete a written informed consent. Patients gender will not be restricted. Informed consent can be obtained by families for those who are not able to write it by themselves.

Exclusion criteria

Exclusion criteria: 1. Previous history of tolvaptan use 2. Contraindication for tolvaptan 3. Unable to take an oral medication 4. Requiring immediate dialysis therapy 5. Pregnant or wish to be pregnant 7. History of major surgery within 60 days 8. History of acute myocardial infarction within 30 days 9. Severe hepatic failure or heart disease 10. Other cases which treating physicians regards as inappropriate for a candidate

Design outcomes

Primary

Measure	Time frame
Urine output after initiating Tolvaptan	—

Countries

Japan

Contacts

Public ContactTomokazu Okado

Tokyo Medical and Dental University Department of Chronic Kidney Disease

tokado.kid@tmd.ac.jp03-5803-5214

Outcome results