liver signal profiling and blood marker research for non-alcoholic fatty liver diseases

liver signal profiling and blood marker research for non-alcoholic fatty liver diseases - liver signal profiling and blood marker research for non-alcoholic fatty liver diseases

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000013323

Enrollment

100

Registered

2014-03-04

Start date

2014-02-28

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nonalcoholic fatty liver diseases

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with suspected NAFLD by interview, blood collection, imaging studies

Exclusion criteria

Exclusion criteria: 1) Persons over 20g per day or 140g per week of alcohol intake 2) Patients who are suspicious of viral hepatitis, autoimmune hepatitis, primary biliary cirrhosis, sclerosing cholangitis, hemochromatosis, alpha1-antitrypsin deficiency, Wilson's disease, drug-induced hepatitis 3) Patients who showed clinical evidence of hepatic decompensation such as hepatic encephalopathy, ascites, variceal bleeding, or a serum bilirubin level greater than twofold the normal upper limit 4) Persons judged inappropriate for this study

Design outcomes

Primary

Measure	Time frame
1) Proceeding Genechip analysis, Methylation BeadChip analysis, and comprehensive analysis of miRNA for signal profiling in liver by using liver biopsy samples collected in each trial sites 2) Proceeding Proteomics analysis, metabolomics analysis, and comprehensive analysis of miRNA to research diagnostic markers for NASH by using blood samples collected in each trial sites	—

Countries

Japan

Contacts

Public ContactYuichiro Eguchi

Saga University Hospital Division of Hepatology

eguchiyu@cc.saga-u.ac.jp0952-34-3010

Outcome results