Effects of chlorogenic acids in hydroxyhydroquinone-reduced coffee on vascular endothelial function in hypertension patients.

Effects of chlorogenic acids in hydroxyhydroquinone-reduced coffee on vascular endothelial function in hypertension patients. - Effects of chlorogenic acids in hydroxyhydroquinone-reduced coffee on vascular endothelial function in hypertension patients.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000013283

Enrollment

Registered

2014-04-01

Start date

2014-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Interventions

Chlorogenic acids in hydroxyhydroquinone-reduced coffee Chlorogenic acids in hydroxyhydroquinone-nonereduced coffee placebo coffee

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: We enrolled mild hypertension patients(systolic blood pressure (SBP): 130 to 159&#8201;mm&#8201;Hg, diastolic blood pressure (DBP): 99&#8201;mm&#8201;Hg or less) without diabetes.

Exclusion criteria

Exclusion criteria: We enrolled the subjects who were not taking statin or renin angiotensin system inhibitors. allergy to coffee pregnancy

Design outcomes

Primary

Measure	Time frame
endothelial function (FMD)	—

Countries

Japan

Contacts

Public ContactHigashi Yukihito

Hiroshima University Hospital Division of Regeneration and Medicine

yhigashi@hiroshima-u.ac.jp+81-82-257-5831

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026