Comparative study of effectiveness gargling "Hange-shashin-to" and azulene sodium sulfonate for oral mucositis which associated with cancer therapy.

Comparative study of effectiveness gargling "Hange-shashin-to" and azulene sodium sulfonate for oral mucositis which associated with cancer therapy. - Comparative study of effectiveness gargling "Hange-shashin-to" and azulene sodium sulfonate for oral mucositis which associated with cancer therapy.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000013281

Enrollment

Registered

2014-03-03

Start date

2014-03-03

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

head and neck cancer, oral cancer

Interventions

Control group: Patients gargles with azulene sodium sulfonate three times a day since treatment start. Hange-shashin-to group: Patients gargles with Hange-shashin-to three times a day since treatment

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients, who suffered from oral cancer or head and neck cancer, planned chemotherapy and chemoradiotherapy.

Exclusion criteria

Exclusion criteria: The patients uses gargling before treatment.

Design outcomes

Primary

Measure	Time frame
Objective evaluation: CTCAE ver.4.0, food requirement, blood examination(total protein, albumin, inflammatory cytokine, etc) Subjective assesment: patients questionnaire	—

Countries

Japan

Contacts

Public ContactNodoka Sekiguchi

Shinshu University Department of Comprehensive Cancer Therapy

nodokas@shinshu-u.ac.jp0263-35-4600

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026

Comparative study of effectiveness gargling &quot;Hange-shashin-to&quot; and azulene sodium sulfonate for oral mucositis which associated with cancer therapy.