The association between the intestinal microenvironment and choleretic effects of Inchinkoto.

The association between the intestinal microenvironment and choleretic effects of Inchinkoto. - The association between the intestinal microenvironment and choleretic effects of Inchinkoto.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000013250

Enrollment

Registered

2014-04-01

Start date

2014-05-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The patients who undergo percutaneous transhepatic biliary drainage (PTBD) or endoscopic nasobiliary drainage (ENBD) due to biliary obstruction.

Interventions

oral intake of Inchinkoto

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Age >=20 2) The patients who undergo percutaneous biliary drainage (PTBD) or endoscopic nasobiliary drainage (ENBD) due to biliary obstruction. 3) The patients who have agreed to participate in the study.

Exclusion criteria

Exclusion criteria: 1) The patients who have rejected to participate in the study. 2) The patients who have been considered to be not eligible for this study by the investigators. 3)The patients who are having other choleretic drugs such as ursodeoxycholic acid.

Design outcomes

Primary

Measure	Time frame
The association between the total bilirubin, direct bilirubin, and bile acid levels in the bile (before and after Inchinkoto administration) and the bacterial concentration, bacterial constitute, fecal organic acid concentration, and pH.	—

Countries

Japan

Contacts

Public ContactYukihiro Yokoyama

Nagoya University Hospital First department of surgery

yyoko@med.nagoya-u.ac.jp052-744-2222

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026