Diabetic low extremity ulcer is one of the refractory wounds and always poses therapeutic challenges.
Conditions
Interventions
patients received a split-thickness autograft combined with ReCell(experimental group)
patients received split-thickness autograft alone (control group)
Sponsors
Department of Burn Surgery The First Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients aged over eighteen years old with a diagnosis of type 1 or type 2 diabetes, who had a diabetic low extremity ulcer last for over four weeks, with a stage 2 by Wagner's scale, and size more than three cm2, absence of vascular reconstruction (ankle brachial indices between 0.7 and 1.2) and had indications of skin grafting were eligible for inclusion
Exclusion criteria
Exclusion criteria: patients with medical conditions that would impair wound healing (e.g. malignancy, autoimmune disease), using corticosteroids or immunosuppressor, a high anesthesiology or surgical risk, uncontrolled hyperglycemia (preoperative HbA1c greater than 12%)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effectiveness | — |
Secondary
| Measure | Time frame |
|---|---|
| safety | — |
Countries
Asia(except Japan)
Contacts
Public ContactZhicheng Hu
The First Affiliated Hospital of Sun Yat-sen University Department of Burn Surgery
Outcome results
None listed