Reactive Attachment Disorder
Conditions
Interventions
Sponsors
University of Fukui, Research Center for Child Mental Development, Division of Psychosocial Support for Nurturing
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients with reactive attachment disorder based on the classifications in the diagnostic and statistical manual of mental disorders (DSM-IV-TR). Healthy children and adolescents with higher level of IQ 80. 2) Subjects within the age range of 8-17 years old. 3) Must demonstrate an acceptable degree of compliance with medication and procedures in the opinion of the investigator.
Exclusion criteria
Exclusion criteria: 1) History of allergy for oxytocin. 2) Subjects who have any other current DSM-IV-TR diagnosis of the following; "Pervasive development disorder", "Attention-deficit/hyperactivity disorder","Schizophrenia and Other Psychotic Disorders","Delirium, Dementia, and Amnestic and Other Cognitive Disorders", "Substance-Related Disorders","eating disorders","personality disorders". 3) Subjects who have a physical disorder with a need of strict diet, or a diagnosis of a severe physical disorder. 4) Women who are breastfeeding, pregnant, possibility of pregnancy, or have a wish of early pregnancy. 5) Subjects who are planned for an immediate therapeutic plan change due to unstable physical or psychological symptoms. 6) Subjects with metalic device in their body. 7) Subjects who, in the Investigator's opinion, might not be suitable for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fMRI analysis : Comparison of brain activity change after oxytocin or placebo administration. | — |
Secondary
| Measure | Time frame |
|---|---|
| plasma oxytocin concentration oxytocin receptor gene polymorphism neuropsychological test | — |
Countries
Japan
Contacts
Public ContactAkemi Tomoda
University of Fukui, Research Center for Child Mental Development Division of Psychosocial Support for Nurturing
Outcome results
None listed