cervical cancer and cervical intraepithelial neoplasia
Conditions
Interventions
Combined conventional cytology and HPV testing will be performed between March 2014 and December 2018 at the Hokkaido University Hospital. Women with both negative cytology result and HVP (-)/non-HPV
Sponsors
Department of Gynecology, Hokkaido University Graduate School of Medicine
Hokkaido Cancer Society Sapporo Medical University Asahikawa Medical University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Women who cooperate with cervical cytology and HPV test sampling. 2. Women who cooperate with colposcopy and punch biopy if necessary. 3. Women who give written informed consent to entering the study after receiving appropriate explanation, with sufficient understanding by her own discretion.
Exclusion criteria
Exclusion criteria: 1. Women who did not consent. 2. Women less than 20 years old 3. Women over 70 years old 4. Women in pregnancy 5. Women who was judged as inappropriate for the study by a doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correspondence of high-risk HPV positivity and HPV16/18 positivity to age, cytological diagnosis (NILM, ASC-US, >=LSIL) and histological diagnosis (>=CIN2, >=CIN3) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Detection rate of cervical lesion (>=CIN2, >=CIN3) by combined cytology and HPV testing as compared to the rate by cytology only which was done in the same period of the research or previously. 2. Incidence of >=CIN2 or >=CIN3 after 3 years in connection with the HPV testing results | — |
Countries
Japan
Contacts
Public ContactNoriaki Sakuragi
Hokkaido University Departments of Obstetrics and Gynecology
Outcome results
None listed