Study of the preventive effect of the sivelestat sodium hydrate for respiratory complications in high-risk patients underwent upper abdominal surgery

Study of the preventive effect of the sivelestat sodium hydrate for respiratory complications in high-risk patients underwent upper abdominal surgery - Preventive effect of sivelestat sodium hydrate for respiratory complications in patients underwent upper abdominal surgery

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000013188

Enrollment

100

Registered

2014-02-18

Start date

2014-02-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper abdominal surgery

Interventions

Perioperative administration of sivelestat sodium hydrate control

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients who are scheduled for (stomach, liver, biliary tract, pancreas) upper abdominal surgery 2) Patients with high probability of postoperative respiratory complications (RFRI> 28 point) 3) Patient with written informed consent

Exclusion criteria

Exclusion criteria: 1) Patients who is not expected curative resection 2) Patients with active infection 3) Patients with a history of drug hypersensitivity to sivelestat sodium hydrate

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative respiratory complications	—

Secondary

Measure	Time frame
1) The frequency of occurrence of postoperative complications 2) Duration of postoperative SIRS 3) Postoperative hospital stay 4) Adverse events	—

Countries

Japan

Contacts

Public ContactKatsunobu Oyama

Kanazawa University Gastroenterologic Surgery

oya-ma@staff.kanazawa-u.ac.jp076-265-2000

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026