Acute and delayed bleeding risk of endoscopic submucosal dissection for gastric neoplasia in patients with low-dose aspirin administration-multicenter randomized control study-

Acute and delayed bleeding risk of endoscopic submucosal dissection for gastric neoplasia in patients with low-dose aspirin administration-multicenter randomized control study- - Multicenter randomized control study for bleeding risk related with LDA during gastric ESD

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000013177

Enrollment

560

Registered

2014-04-01

Start date

2014-06-23

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric neoplasia

Interventions

low-dose aspirin continuous administration low-dose aspirin withdrawal

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Diagnosed ad gastric adenoma or gastric cancer estimated as clinical stage IA endoscopically/Administrating low-dose aspirin/More than 9.0d/dl Hb level on the laboratory data within 28 days before ESD/Physical status;0-2/Accepted to enrollment and registration for this randomized study

Exclusion criteria

Exclusion criteria: Subject with difficult agreement of enrollment and registration for this randomized study/Ineligible subjects certified by doctors

Design outcomes

Primary

Measure	Time frame
Incidence rate of active bleeding during ESD and delayed bleeding post ESD in patients with gastric neoplasia	—

Secondary

Measure	Time frame
incidence of cerebrovascular event, healing status of mucosal defect after ESD, incidence of any adverse events, incidence of adverse event related with ESD, treatment time	—

Countries

Japan

Contacts

Public ContactHideki ISHIKAWA

Graduate School of Medical Science, Kyoto Prefectural University of Medicine Department of Molecular-Targeting Cancer Prevention

cancer@gol.com06-6202-5444

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026