esophageal cancer
Conditions
Interventions
Sedative status during ESD by administering Cercin and opistan
Sedative status during ESD by administering Precedex
Sponsors
Department of Gastroenterology, Toranomon Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Squamous cell carcinoma histologically 2)SM2 or less tumor invasion as a preoperative diagnosis 3)no lymph node or distant metastasis by CT 4)obtained written informed consent 5)performance status is 0-2 6)no severe organ dysfunction
Exclusion criteria
Exclusion criteria: 1)uncontrollable DM 2)uncontrollable HT 3)uncontrollable heart disease 4)severe or uncontroallable respiratory disease 5)acute alcoholoic addiction 6)epilepsy 7)oxygen is needed in walking or at rest 8)active bacterial of fungal infection 9)pregnancy 10)psychiatric disease 11)alcoholic liver cirrhosis 12)allergy to opistan 13)administered monoamin oxidase inhibitor 14)acute narrow-angle glaucoma 15)myasthenia gravis 16)administered ritonavir
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| body movement during ESD | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.the frequency of hypotention 2.the frequency of bradycardia 3.the frequency of respiratory depression 4.the frequency of complication due to ESD 5.the relationship between repiratory rate and saturation 6.awareness after ESD 7.the number of discontinuation of Precedex 8.sedative level during ESD | — |
Countries
Japan
Contacts
Public ContactToshiro Iizuka
Toranomon Hospital Department of Gastroenterology
Outcome results
None listed