Postoperative pain control in Opioid Tolerant patients -Efficacy of the use of iv Oxycodone -

Postoperative pain control in Opioid Tolerant patients -Efficacy of the use of iv Oxycodone - - Postoperative pain and Opioid Tolerance

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000013075

Enrollment

Registered

2014-02-05

Start date

2014-02-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative cancer pain

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Cancer patient for surgery treatment 2) Pain controlled by oxycodone or fentanyl for over 1 month 3) Age over 20 yrs old 4) ASA Physical status 1 or 2 5) Not pregnant 6) Informed consent by his/her own will

Exclusion criteria

Exclusion criteria: 1) Opioid treatment for non-cancer pain 2) Hepatic failure (AST or ALT >300IU) 3) Renal failure (BUN>50 Cre>3.0) 4) Pregnant or breast feeding patient 5) Not applicable determined by the Dr responsible for the trial.

Design outcomes

Primary

Measure	Time frame
Effective pain control (Numerical Rating Scale at rest <5) with calculated opioid dose.	—

Secondary

Measure	Time frame
1.Safety determined from the frequency of side-effects (respiratory depression, nausea, itching) in need of treatment. 2. Use of pain and respiratory threshold measurement in the calculation of opioid dosage. 3.Determination of Oxycodone po to iv ratio.	—

Countries

Japan

Contacts

Public ContactNatsuko Nozaki-Taguchi

Chiba University Hospital Department of Anesthesiology and Palliative Medicine

nnoztag@faculty.chiba-u.jp043-226-2303

Outcome results