scabies
Conditions
Interventions
After preparing Ivermectin bath solution that 4 tablets of Stromectol put into 150 liters of hot water with baby bath agent, volunteer takes the bath for from 5 to 15minutes. Then, the state of the sk
Sponsors
Tokyo University of Science
Kikkoman General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Healthy and over age of 20 2) Have written consent on subjects' free will after being completely explained about this study
Exclusion criteria
Exclusion criteria: 1) The patient who has an obstacle in the barrier of the skin according to a skin disorder 2) Those who have the following diseases in the past or the present - Liver disease - The disease considered to affect a test result by a doctor in attendance in addition to this, or the disease considered that medication of ivermectin brings about a disadvantage 3) The superfluous ingestion person of the coffee containing caffeine, or a drink (>8 cup / day) 4) The abuse person of medicine or alcohol 5) The addict of an illegal drug 6) The woman who offered the blood of 400mL within the man and woman who offered the blood of 200mL within four weeks before the examination or the man who offered the blood of 400mL within 12 weeks, and 16 weeks 7) Those who participated in four weeks to the clinical test using other investigational new drugs before this start of test 8) Those who have an anamnesis of hypersensitivity in the ingredient of a StromectolⓇ Tablets or the charge of baby purification (Pigeon, Inc.) 9) The woman during pregnancy or potential pregnancy, and breast-feeding 10) Those whom the examination doctor in attendance judged to be unsuitable as a subject 11) Those who have used medication within a week
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| -The concentration of Ivermectin in horny layer -The concentration of Ivermectin in blood | — |
Secondary
| Measure | Time frame |
|---|---|
| -The concentration of Ivermectin in the bath solution -Toxic Epidermal necrosis -Stevens-Johnson syndrome -Impairment of liver function -Other adverse events | — |
Countries
Japan
Contacts
Public ContactMasayo Komoda
Tokyo University of Science Faculty of Pharmaceutical Sciences
Outcome results
None listed