Helicobacter infection without other orgnic disease
Conditions
Interventions
For upper abdominal symptoms of Helicobacter pylori (H. pylori) infected patients, proton pump inhibitor (PPI) are administrated before the eradication of H. pylori. If the upper abdominal symptoms we
Sponsors
Kagoshima University Graduate School of Medical and Dental Sciences, Digestive and Life-style related Disease
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who are not administrated proton pump inhibitor (PPI) or administrated half dose of PPI. Patients who are diagnosed atrophic gastritis with endoscopy.
Exclusion criteria
Exclusion criteria: Patients who are not diagnosed gastro-esophageal reflux disease (GERD) over the grade A of Los Angeles Classification, gastric ulcer, gastric cancer. Patients who are not administrated non steroidal anti-inflammatory drugs (NSAIDs), major or minor tranquilizer, acotiamide every day. Patients with history of gastrectomy. Patients with severe renal or liver dysfunciton. Patients with cancer. Patients who have a history of failure of the first eradication of Helicobacter pylori.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of quality of life before and after Helicbacter pylori eradication | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Effect of full dose of administration of proton pump inhibitor for upper abdominal symptoms in before and after eradication of Helicobacter pylori. 2.Evaluation of the successful rate of eradication of Helicobacter pylori by preceding PPI administration before eradication. | — |
Countries
Japan
Contacts
Public ContactHiroki Taguchi
Kagoshima University Graduate School of Medical and Dental Sciences Digestive and Life-style related Disease
Outcome results
None listed