Topical Isopropyl Unoprostone for Rhegmatogenous Retinal Detachment: Pilot Study

Topical Isopropyl Unoprostone for Rhegmatogenous Retinal Detachment: Pilot Study - Topical Isopropyl Unoprostone for Rhegmatogenous Retinal Detachment

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000013051

Enrollment

Registered

2014-03-01

Start date

2015-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rhegmatogenous retinal detachment

Interventions

Unoprostone eye drops 0.15% placebo eye drops

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: macula-off rhegmatogenous retinal detachment best-corrected visual acuity <0.3 duration of macula-off retinal detachment < 1week after successful vitrectomy

Exclusion criteria

Exclusion criteria: severe cataract macular disease including pathologic myopia past history of retinal detachment past history of intraocular surgery glaucoma, neuropathy allegy to Unoprostone past history of topical Unoprostone pregnancy, breast feeding severe cardiovascular disease, renal feilure, uncontrolled diabetes

Design outcomes

Primary

Measure	Time frame
Best-corrected visual acuity	—

Secondary

Measure	Time frame
retinal sensitivity thickness of outer nuclear layer macular volume fundus auto fluorescence VFQ-25 color sense	—

Countries

Japan

Contacts

Public ContactTakayuki Baba

Chiba University Graduate School of Medicine Ophthalmology and Visual Science

babatakayuki@nifty.com043-222-7171

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026