intercostal neuralgia
Conditions
Interventions
treatment group (Duloxetine group)
Sponsors
Kobe University Graduate School of Medicine, Kobe, Japan
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: patients who are more than 30 mm in VAS patients who are more than 11 points in BDI (1) patients who are ages 20-80 (2) patients who are PS 0, 1 (ECOG) (3) patients who undergo thoracoscopic surgery for lung cancer (4) patients who have normal kidney function with creatinine clearance >30ml/min (5) patients who have signed the consent form to participate in this study
Exclusion criteria
Exclusion criteria: (1) patients who have been taking antidepressants, anticonvulsant, opoids, and NSAIDs before surgery (2) patients who have serious complications (such as uncontrollable heart, lung, liver or kidney disease, and diabetes) (3) patients who have a history of peptic ulcer, aspirin-induced asthma, closed angle glaucoma (4) patients who are pregnant, are nursing, or might be pregnant (voluntary) (5) patients who handle hazardous machinery, such as driving a car (6) patients who are considered unsuitable for the study by the primary physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Control rate of pain and depression after surgery; BDI and VAS on the three week and five week after administration for depression symptom associated with intercostal neuralgia after thoracoscopic surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| QOL improvement evaluated by BPI. General condition improvement evaluated by CGI. | — |
Countries
Japan
Contacts
Public ContactDaisuke Hokka
Kobe University Graduate School of Medicine, Kobe, Japan Division of Thoracic Surgery, Department of Surgery
Outcome results
None listed