A multicenter study of clinical usefulness of flow-mediated vasodilation C

Conditions

Healthy subjects, or patients with cardiovascular risk factor or established cardiovascular disease

Yamaji T, Yusoff FM, Kishimoto S, Kajikawa M, Yoshimura K, Nakano Y, Goto C, Harada T, Mizobuchi A, Tanigawa S, Maruhashi T, Higashi Y.

2023-12-256 citations

10.1016/j.jacl.2023.12.006

Short stature is associated with low flow-mediated vasodilation in Japanese men.

Harada T, Kajikawa M, Maruhashi T, Kishimoto S, Yamaji T, Han Y, Mizobuchi A, Hashimoto Y, Yoshimura K, Nakano Y, Chayama K, Goto C, Yusoff FM, Nakashima A, Higashi Y.

2021-11-043 citations

10.1038/s41440-021-00785-0

A body shape index is associated with endothelial dysfunction in both men and women.

Kajikawa M, Maruhashi T, Kishimoto S, Yamaji T, Harada T, Hashimoto Y, Han Y, Mizobuchi A, Aoki G, Yoshimura K, Chayama K, Goto C, Yusoff FM, Nakashima A, Higashi Y.

2021-09-0914 citations

10.1038/s41598-021-97325-0

Inconvenient relationship of haemoglobin A1c level with endothelial function in type 2 diabetes in a cross-sectional study

Takayuki Yamaji, Takahiro Harada, Yu Hashimoto, Yuji Takaeko, Masato Kajikawa et al. (16 authors)

BMJ Open2021-06-016 citations

10.1136/bmjopen-2020-045415

Endothelial function is preserved in light to moderate alcohol drinkers but is impaired in heavy drinkers in women: Flow-mediated Dilation Japan (FMD-J) study

Nozomu Oda, Masato Kajikawa, Tatsuya Maruhashi, Shinji Kishimoto, Farina Mohamad Yusoff et al. (11 authors)

PLoS ONE2020-12-0315 citations

10.1371/journal.pone.0243216

Pre-impaired fasting glucose state is a risk factor for endothelial dysfunction: Flow-mediated Dilation Japan (FMD-J) study

Takayuki Yamaji, Takahiro Harada, Yu Hashimoto, Yuji Takaeko, Masato Kajikawa et al. (15 authors)

BMJ Open Diabetes Research & Care2020-10-0119 citations

10.1136/bmjdrc-2020-001610

Association of Body Mass Index with Endothelial Function in Asian Men.

Kajikawa M, Maruhashi T, Kishimoto S, Hashimoto H, Takaeko Y, Yamaji T, Harada T, Hashimoto Y, Han Y, Kihara Y, Hida E, Chayama K, Goto C, Yusoff FM, Nakashima A, Higashi Y.

2020-09-128 citations

10.1016/j.ijcard.2020.09.029

Diagnostic Criteria of Flow‐Mediated Vasodilation for Normal Endothelial Function and Nitroglycerin‐Induced Vasodilation for Normal Vascular Smooth Muscle Function of the Brachial Artery

Tatsuya Maruhashi, Masato Kajikawa, Shinji Kishimoto, Haruki Hashimoto, Yuji Takaeko et al. (39 authors)

Journal of the American Heart Association2020-01-08122 citations

10.1161/jaha.119.013915

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The study subjects are employees of an electronics and chemical company who undergo annual health checkups mandated by the company.

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

Measure	Time frame
1) FMD, 2) PWV, ABI, serum C-reactive protein, proteomic biomarkers, ultrasound examination of the carotid artery [max intima-media thickness (IMT), mean IMT], arterial stiffness, and micaroalbuminuria.	—

Countries

Japan

Contacts

Public ContactYukihito Higashi

Research Institute for Radiation Biology and Medicine Department of Cardiovascular Regeneration and Medicine

yhigashi@hiroshima-u.ac.jp082-257-5831

Outcome results