Renal anemia on hemodialysis patients
Conditions
Interventions
treated epoetin beta pegol once-monthly for one year
treated epoetin beta pegol twice-monthly for one year
Sponsors
kanazawa medical university medical research institute,Division of Aging Research
Chuno Kosei Hospital Division of Nephrology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.patients who receive three times a week of hemodialysis more than three months 2.patients treated with 50-200 CERA per month 3.patients who hemoglobin density of 3 months undergoes a change of at 10-12 g/dL in the past 4.patients that clear iron lack is not accepted in the past three months (Ferritin over 50 ng/mL) 5.20 years old or older 6.patients who acccept this study
Exclusion criteria
Exclusion criteria: 1.patients who do not accept this study 2.patients who have allergy for ESA 3.patients who have uncontrollable high blood pressure 4.patients with factors that could have a clear impact on hemoglobin concentration, such as infectious diseases, malignant tumors, bleeding of moderate or more 5.women who are pregnant,breastfeeding,possibly pregnant,or not willing to use birth control in the period leading up to the end of the study at the time of obtaining informed consent 6.patients who received red bllod cell transfusion within 3 months before enrollment 7.patients who are judged ineligible by the physician in charge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| (1) biological parameters of iron metabolism(including Hep-25) (2) ERI(ESA Resistance Index) at endpoint (3) pecentage of maintaing the target Hb level for one year | — |
Countries
Japan
Contacts
Public ContactShogo Kimura
Chuno Kosei Hospital Division of Nephrology
Outcome results
None listed