A randomized control trial of UNAHATAKE herb extract intake on anti- glycation effect and improvement in skin.

A randomized control trial of UNAHATAKE herb extract intake on anti- glycation effect and improvement in skin. - Anti-glycation effect of "herb extract" on human skin.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000012820

Enrollment

Registered

2014-01-14

Start date

2014-01-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-menopausal middle-aged female

Interventions

Test group Oral intake of capsules with 300mg UNAHATAKE herb extract after breakfast for 12 weeks Control group Oral intake of capsules without UNAHATAKE herb extract after breakfast for 12 weeks

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Post-menopause healthy Japanese women ages 45 or more and less than 65 years old

Exclusion criteria

Exclusion criteria: 1) Persons less than 2 years after menopause 2) Smoking persons 3) Users of anti-glycation materials 4) Users of medicines or supplements affecting blood glucose 5) Persons with severe dysfunction of liver, kidney or heart 6) Persons with food allergy or allergic dermatitis 7) Persons who received gastrointestinal surgery 8) Persons with high BMI more than 30

Design outcomes

Primary

Measure	Time frame
Skin elasticity, skin CML, skin AGEs accumulation, skin color, skin image analysis by VISIA, fasting plasma glucose, insulin, CML, 3-deoxyglucosone, pentosidine, questionnaire	—

Countries

Japan

Contacts

Public ContactKeiichi Naito

A-kit Corporation Life and Medical Sciences Inspection center

naito@a-kit.co.jp072-646-7761

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026