StageII(high risk) and stageIIIa resectable colorectal cancer
Conditions
Interventions
Capecitabine 5-days on/ 2-days off schedule
Sponsors
Tsukasa Hotta
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Histopathological diagnosis of stage II(high risk) and IIIa colorectal cancer 2.curable resection 3.more than 20 yeras old 4.ECOG Performance Status 0-2 5.WBC more than 3000/mm3, neutrophil more than 1500/mm3, Platelet more than 10x104/mm3, Hb more than 9g/dL, TBil less than 1.5mg/dL, AST and ALT less than 100IU/L Cr less than 1.5mg/dL, 6. it is possible to perform adjuvant chemotherapy within 8 weeks after tumor resection 7.informed consent
Exclusion criteria
Exclusion criteria: 1.Pregnant female 2.It may be pregnant state female 3.Past history of malignant disease 4.There is uncontrolled cerebrovascular disease 5.There was serious allergy for fluorouracl related drug 6.There was allergy due to the lack of DPD 7.There is uncontrorable infection disease 8.It is difficult to intake oral food 9.Judgementof study controlled doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence rate of side effect | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease free survival, safety, proportion of treatments completed, quality of life. | — |
Countries
Japan
Contacts
Public ContactTsukasa Hotta
Wakayama Medical University, School of Medicine Second Department of Surgery
Outcome results
None listed