Chronic obstructive pulmonary disease (COPD)
Conditions
Interventions
Tulobuterol Patch ADL, exercise tolerance
Sponsors
Juntendo University Faculty of Medicine and graduate School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Subjects: COPD patients COPD was diagnosed based on the patient medical history, spirometry, and radiologic findings, including high-resolution computed tomography of the chest according to Global Initiative for Chronic Obstructive Lung Disease(GOLD) guideline. Inclusion criteria included the presence of moderate to severe COPD, including post-bronchodilator forced expiratory volume in 1s (FEV1)/forced vital capacity (FVC) ratio of <70% and percent predicted FEV1 (%FEV1) <80%. Only patients whose condition had remained stable for >= 1 month more were eligible.
Exclusion criteria
Exclusion criteria: Patients with any of the following were excluded: 1)Bronchial asthma 2)Respiratory tract infection within the preceding 4 weeks 3)Respiratory failure with home oxygen therapy 4)who required oral corticosteroids 5)hypertension, heart disease, thyroid disease, diabetes, or skin disease and patients contraindicated to beta-2 agonists 6)Pregnant 7)others contraindicated to exercise
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement for dyspnea in COPD patients in diary living and exercise activities | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement for pulmonary function value in COPD | — |
Countries
Japan
Contacts
Public ContactYuzo Kodama
Juntendo University Scool of Medicine Respiratory Medicine
Outcome results
None listed