Diabetic cardiomyopaty and diabetes with normal cardiac function as controls
Conditions
Interventions
None listed
Sponsors
Tokyo Women's Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Diabetic patients who are followed up in diabetic center or Heart center in Tokyo Women's medical university. Inclusion criteria is normal cardiac function and no coronary stenosis in diabetic controls, and low LVEF< 45 % and no coronary stenosis in DMCM.
Exclusion criteria
Exclusion criteria: Severe renal dysfunction (CKD stage>=4) Patients with other multiple complication who are unlikely to undergo proposed examinations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We analyze difference in myocardial blood flow (MBF) at rest and stress, and myocardial flow reserve (MFR) as determined by ammonia-13 PET, cardiac function and size of LGE as determined by cardiac MRI between patients with DMCM and diabetes control. | — |
Secondary
| Measure | Time frame |
|---|---|
| We analyze relationship between coronary calcification and MBF and MFR. In diabetes controls, we compare the MBF and MFR with clinical characteristics such as HbA1c, fasting glucose, plasma cholesterol and diabetic history. | — |
Countries
Japan
Contacts
Public ContactMitsuru Momose
Tokyo Women's Medical University Dept.of Diagnostic Imaging and Nuclear Medicine
Outcome results
None listed