VDT-related dry eye
Conditions
Interventions
3% diauafosol sodium eye drops 6 times a day
2% rebamipide eye drops 4 times a day
Sponsors
Department of Ophthalmology, Tokyo Dental College Ichikawa General Hospital
Shimazaki Eye Clinic, Ichikawa Shapo Eye Clinic, Iidabashi Eye Clinic, Shinjuku Eye Clinic, Ryogoku Eye Clinic, Smile Eye Clinic
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Daily VDT workers (>4 hours a day in average) 2) "definite dry eye" or "dry eye suspects" according to the Japanese dry eye criteria in 2006 3) More than mild subjective symptom score by DEQS (dry eye-related quality of life score) 4) No dry eye eye drops for the last 2 weeks or stably used for more than 2 weeks
Exclusion criteria
Exclusion criteria: 1) Daily contact lens user 2) History of diquafosol or rebamipide uses in the last 1 month prior to the initiation of the study 3) Anatomical or functional abnormalities in the eye (ex. lid closure abnormality) 4) History of ophthalmic surgeries for the last 3 months 5) History of lacrimal punctal plug or occlusion 6) Allergy to diauafosal or rebamipide 7) Other conditions that may influence of the assessment of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1 Changes in symptom scores at 4th week 2 Changes in tear-film break-up time (BUT) at 4th week 3 Changes in maximum opening time (MOT) at 4th week | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 Changes in MOT-BUT difference at 4th week 2 Changes in corneal and conjunctival epithelial damage scores at 4th week 3 Changes in subjective scores, BUT, MOT, BUT-MOT difference, and epithelial damage scores at 2nd and 8th weeks 4 Questionnaire | — |
Countries
Japan
Contacts
Public ContactJun Shimazaki
Tokyo Dental College Ichikawa General Hospital Department of Ophthalmology
Outcome results
None listed