Healthy subjects Pre-diabetes
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: <Healthy subjects> 1) Aged 20 - 64 years 2) Capable of giving informed consent <Pre-diabetes> 1) Aged 20 - 64 years 2) Fasting glucose not less than 100 mg/dL, under 126 mg/dL, or HbA1c not less than 5.7%, under 6.5% 3) Capable of giving informed consent
Exclusion criteria
Exclusion criteria: <Healthy subjects> 1) BMI over 25 kg/m2 2) Fasting glucose not less than 100 mg/dL 3) HbA1c not less than 5.7% 4) Triglyceride not less than 150mg/dL, HDL cholesterol less than 40mg/dL, LDL cholesterol not less than 140mg/dL 5) Subjects who is using medicines for treatment of chronic diseases 6) Current smokers 7) Subjects who are diagnosed anemia. Male; red blood cells less than 4.27 x 106/uL, hemoglobin less than 12.0g/dL, hematocrit less than 33.5%. Female; red blood cells less than 3.76 x 106/uL, hemoglobin less than 14.0g/dL, hematocrit less than 40.0%. 8) Subjects who were recognized unsuitable for this study by the Investigator. <Pre-diabetes> 1) Subjects who are received pharmacotherapy for diabetes. 2) Current smokers 3) Subjects who are diagnosed anemia. Male; red blood cells less than 4.27 x 106/uL, hemoglobin less than 12.0g/dL, hematocrit less than 33.5%. Female; red blood cells less than 3.76 x 106/uL, hemoglobin less than 14.0g/dL, hematocrit less than 40.0%. 4) Subjects who were recognized unsuitable for this study by the Investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| glycemic index (GI) | — |
Secondary
| Measure | Time frame |
|---|---|
| insulin, GLP-1, GIP, triglyceride | — |
Countries
Japan
Contacts
University of Tsukuba, Faculty of Medicene Course of clinical research and regional innovation donated by the Japan Agriculture Ibaraki Public