The effect of preoperative oral nutritional supplement (ONS) on the prognostic nutritional Index (PNI) in patients undergoing gastrectomy for gastric cancer

The effect of preoperative oral nutritional supplement (ONS) on the prognostic nutritional Index (PNI) in patients undergoing gastrectomy for gastric cancer - The effect of preoperative ONS on the PNI in patients undergoing gastrectomy for gastric cancer

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000012597

Enrollment

Registered

2013-12-17

Start date

2013-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric cancer

Interventions

In addition to a meal, an enteral nutrient (Racol&amp

#174

NF) is administered 3 times per day (600 kcal / day) for 20 days or longer before the operation.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Histologically confirmed gastric cancer (2) No prior chemotherapy (3) An age of 20 - 80 (4) A PNI of <48 (5) An Eastern Cooperative Oncology Group (ECOG) performance status (PS) of 0-2 (6) Sufficient function of the liver, kidney and bone marrow (7) Sufficient oral intake (8) Written informed consent

Exclusion criteria

Exclusion criteria: (1) Preoperative chemotherapy or chemoradiotherapy (2) Severe bowel obstruction (3) Short-bowel syndrome (4) Severe liver or renal dysfunction (5) Uncontrolled diabetes mellitus (6) Congenital amino acid abnormalities (7) Milk protein allergy or soy protein allergy (8) Electrolyte abnormalities (9) Pregnancy or insufficient contraception (10) Severe mental disease

Design outcomes

Primary

Measure	Time frame
Change of the PNI	—

Secondary

Measure	Time frame
(1) Nutritional status (2) Body weight and body mass index (3) Performance status (4) Adverse events	—

Countries

Japan

Contacts

Public ContactTomoyoshi Takayama, MD

Nara Medical University Department of Surgery

t-taka@naramed-u.ac.jp0744-29-8863

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026