anti-cytokine therapy for discogenic low back pain

anti-cytokine therapy for discogenic low back pain - ACDLP

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000012566

Enrollment

Registered

2013-12-12

Start date

2011-10-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

discogenic low back pain

Interventions

1.intradiscal administration of local anesthetic agent group 2.intradiscal administration of local anesthetic agent and anti-TNFa inhibitor group 3.intradiscal administration of local anesthetic

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.low back pain 2.X-ray and MRI can explain the condition 3.less than 2 disc degeneration 4.agreement with this study 5.refractory to 3 months of conservative treatments

Exclusion criteria

Exclusion criteria: 1.loss of consiousness 2.case with history of spinal surgery, infection 3.severe systemic complications 4.diabetes mellitus 5.psychiatric disease 6.pregnant women and women suspected of being pregnant 7.case with malignancy 8.the case considered to be unsuitable as a subject

Design outcomes

Primary

Measure	Time frame
1. analgesic effect 2. adverse events	—

Countries

Japan

Contacts

Public ContactTakeshi Sainoh

Graduate School of Medicine, Chiba University Department of Orthopaedic Surgery

sain3005@yahoo.co.jp043-226-2117

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026