bacterial infection
Conditions
Interventions
Additional 1.5 ml of blood sample will be withdrawn to analyze presepsin and other markers at the routine blood examination.
Sponsors
Faculty of Medicine, Osaka Medical College
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Feverish patients need blood analysis to rule out bacterial infections in the pediatric emergency division and pediatric outpatient clinic. Fever is defined as the presence of an axillary temperature >=38 degree C. Serious bacterial infection is defined as the presence of bacteremia, urinary tract infection, pneumonia, meningitis, osteomyelitis, septic arthritis and/or sepsis. All patients or their guardians are required to sign a consent form.
Exclusion criteria
Exclusion criteria: Patients who have 1) received antibiotic treatment within 48 hours , 2) a fever caused by vaccination, 3) had surgery within 7 days , and 4) a fever lasting longer than 3 days before admission and patients considered ineligible for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Study 1. To evaluate the cut-off value of presepsin in the diagnosis and assessment of pediatric bacterial infections. Study 2. To evaluate the correlation between clinical symptoms and white-blood cell count, absolute neutrophil count, C-reactive protein, procalcitonin, Interleukin 6 and presepsin levels. | — |
Countries
Japan
Contacts
Public ContactMasahiko Nitta
Faculty of Medicine, Osaka Medical College Department of Emergency Medicine
Outcome results
None listed