An immunohistological study of the human skin before and after application of cosmetic lotions containing various molecular sizes of hyaluronan and a supplementary study about ability of steroid production in epidermis by application of ACTH.

An immunohistological study of the human skin before and after application of cosmetic lotions containing various molecular sizes of hyaluronan and a supplementary study about ability of steroid production in epidermis by application of ACTH. - Immunohistological changes of human skin by hyaluronan lotion and the epidermis ACTH loading test.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000012511

Enrollment

Registered

2013-12-31

Start date

2014-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

1.aged skin 2.atopic dermatitis

Interventions

External application of hyaluronan lotion twice a day for two weeks. External application of ACTH solution also twice a day for two weeks in patients with atopic dermatitis.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Eligible over 60 years old in aged skin subjects.

Exclusion criteria

Exclusion criteria: Ineligible under 60 years old in aged skin subjects.

Design outcomes

Primary

Measure	Time frame
Immunohistological changes before and after application of hyaluronan lotion for two weeks.	—

Secondary

Measure	Time frame
Immunohistological changes before and after application of ACTH lotion for two weeks.	—

Countries

Japan

Contacts

Public ContactMototsugu Fukaya

Tsurumai Kouen Clinic Cosmetic surgery and dermatolgy

moto@earth.ocn.ne.jp+81-52-264-0212

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026