Evaluation of maximum cross-section of extraocular muscles and orbital fat volume using 3T MRI.

Evaluation of maximum cross-section of extraocular muscles and orbital fat volume using 3T MRI. - Evaluation of maximum cross-section of extraocular muscles and orbital fat volume using 3T MRI.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000012492

Enrollment

Registered

2013-12-04

Start date

2013-11-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thyroid-associated ophthalmopathy extraocular muscular atrophy

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients: (a) People twenty years old and over at the time of the consent. (b) patients with thyroid-associated ophthalmopathy of extraorbiral muscular atrophy. (c) people who don't have other orbital abnormality. (d) People who can consent to this study in writing. control: (a) People twenty years old and over at the time of the consent. (b) people who don't have any orbital abnormality. (c) People who can consent to this study in writing.

Exclusion criteria

Exclusion criteria: (a) Contraindication to MRI(cardiac pacemaker; cochlear implantation device; defibrillator; neurostimulator; bone growth stimulation device; infusion pump; deep brain stimulation; cervical artery crump(Poppen-Blaylock); chip of ferromagnetic substance in eyeball, brain, internal organs, lung, mediastinum; intraaortic filter, intravascular coil or stent within 2 months, claustrophobia, tattoo, pregnancy or likelihood of pregnancy) (b) People who were unsuitable for this study.

Design outcomes

Primary

Measure	Time frame
A comparison of maximum cross-section of extraocular muscles and orbital fat volume of patients with thyroid-associated ophthalmopathy at before and after treatment.	—

Secondary

Measure	Time frame
(a) The association between CAS (clinical activity score) and maximum cross-section of extraocular muscles/ orbital fat volume of patients with thyroid-associated ophthalmopathy. (b) A comparison of maximum cross-section of extraocular muscles between patients with thyroid-associated ophthalmopathy, patients with extraorbital muscular atrophy and controls. (c) A comparison of orbital fat volume between patients with thyroid-associated ophthalmopathy and controls.	—

Measure

Time frame

(a) The association between CAS (clinical activity score) and maximum cross-section of extraocular muscles/ orbital fat volume of patients with thyroid-associated ophthalmopathy. (b) A comparison of maximum cross-section of extraocular muscles between patients with thyroid-associated ophthalmopathy, patients with extraorbital muscular atrophy and controls. (c) A comparison of orbital fat volume between patients with thyroid-associated ophthalmopathy and controls.

—

Countries

Japan

Contacts

Public ContactYoko Kaichi

Institute of Biomedical and Health Sciences, Hiroshima University Diagnostic Radiology

kaichi@hiroshima-u.ac.jp082-257-5257

Outcome results