Effect of Sitagliptin on Myocardial function in type-2 diabetic patients complicated by congestive heart failure

Effect of Sitagliptin on Myocardial function in type-2 diabetic patients complicated by congestive heart failure - Effect of Sitagliptin on Myocardial function in type-2 diabetic patients complicated by congestive heart failure

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000012490

Enrollment

Registered

2014-01-01

Start date

2014-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type-2 diabitic patients with heart failure

Interventions

Patients who undergo poor blood sugar control despite on sufficient dose of sulfonyl urea antidiabetic drug

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with chronic heart failure (NYHA functional class II or III) who are under poor control despite receiving sulfonyl urea based antidiabetic medication for 3 months with a HbA1c of 6.5% and more

Exclusion criteria

Exclusion criteria: 1) type I diabetes 2) Uncontrolled hypertension 3) patiens who experienced myocardial infarction, coronay bypass surgery, stroke, TIA within 3 months prior to the participation 4) patiens who experienced ketosis or diabetic coma for the past 6 months 5) patients with severe infectious disease, major surgery, and trauma4 6) serum creatinine level of 1.5 mg/ml and more 7) on insuline 8) on pregnancy 9) allergic to sitagliptin

Design outcomes

Primary

Measure	Time frame
Changes in systolic and diastolic cardiac funciton	—

Countries

Japan

Contacts

Public ContactTakahide Ito

Osaka Medical College Department of Cardiology

in3016@poh.osaka-med.ac.jp072-683-1221

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026