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Study of Algorithm for Post-stroke Patients to improve oral intake Level

Study of Algorithm for Post-stroke Patients to improve oral intake Level - APPLE study

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000012475
Enrollment
60
Registered
2013-12-09
Start date
2013-12-09
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute stroke

Interventions

Oral care Indirect training for dysphagia Repetitive saliva swallowing test, RSST Modified water swallow test, MWST Food test, FT Direct training for dysphagia

Sponsors

Iwate Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. NIHSS of 10 to 30 on admission 2. mRS of 0 or 1 prior stroke onset 3. Patients who can orally take three meals per a day and do not need to be thickened for water intake prior stroke onset

Exclusion criteria

Exclusion criteria: 1. Patiens with supra-tentorial and infra-tentorial stroke lesions. 2. Patients with subarachnoid hemorrhage 3. Patients with severe aspiration pneumonia or suffocation on admission. 4. Patients with severe damage of digestive tract function due to inflammatory bowel disease or short bowel syndrome, etc. 5. Patients with impossible oral intake due to severe dysphagia caused by organic disorder, dementia or drugs prior stroke onset. 6. Patients who are decided by physicians as being inappropriate for entry into the present study

Design outcomes

Primary

MeasureTime frame
Incidence of development of aspiration pneumonia during hospitalization

Secondary

MeasureTime frame
1. Oral intake level (grade of oral intake and degree of dysphagia on discharge; presence or absence of oral intake during hospitalization; term from admission to start of oral intake) 2. Nutrition indicators (chronological changes of BMI, albumin, total protein, total count of lymphocyte)

Countries

Japan

Contacts

Public ContactKuniaki Ogasawara

Iwate Medical University Department of Neurosurgery

kuogasa@iwate-med.ac.jp019-651-5111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026