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Differential intervention of sodium polystyrene sulfonate versus calcium polystyrene sulfonate in patients with chronic kidney disease and hyperkalemia

Differential intervention of sodium polystyrene sulfonate versus calcium polystyrene sulfonate in patients with chronic kidney disease and hyperkalemia - Differential intervention of sodium polystyrene sulfonate versus calcium polystyrene sulfonate in patients with chronic kidney disease and hyperkalemia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000012443
Enrollment
120
Registered
2013-12-01
Start date
2013-12-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease with hyperkalemia

Interventions

Sodium polystyrene sulfonate Calcium polystyrene sulfonate

Sponsors

Shonan Kamakura General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who meets all the following standards 1)Patients with hyperkalemia(serum potassium is 5.5mEq/L or more) or receiving ion exchange resin for hyperkalemia 2)Outpatient 3)Patients with chronic kidney disease(stage G3-G5) 4)Patients over 20 years old at the time of giving consent 5)Patients giving written consent after being provided with sufficient explanation about participation in this clinical trial

Exclusion criteria

Exclusion criteria: Patients who corresponds to either of the following cannot participate in this clinical study 1)Patients on dialysis 2)Patients receiving oral hypoglycemic agents that might influence the insulin resistance (thiazolidine, biguanide, DPP-4 inhibitors, and drug combination comprising these component), insulin preparation, or GLP-1 receptor agonists 3)Patients who are allergic to targeted medication 4)Patients with intestinal obstruction

Design outcomes

Primary

MeasureTime frame
Serum potassium level

Secondary

MeasureTime frame
1)Serum bicarbonate level 2)Arteriosclerosis-related examination (coronary calcification score, and pulse wave velocity) 3)Insulin resistant (HOMA-R)

Countries

Japan

Contacts

Public ContactMachiko Oka

Shonan Kamakura General Hospital Dept. of Nephrology, Immunology and Vascular Medicine

machiko.oka@tokushukai.jp0467-46-1717

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026