acute rhinosinusitis
Conditions
Interventions
Garenoxacin 400mg once daily for 7-14day
Levofloxacin 500mg once daily for 7-14day
Sponsors
Hokuriku otolaryngology practiced expert study group
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Outpatients with a diagnosis of moderate to severe acute rhinosinusitis of presumed bacterial origin have symptoms of acute sinusitis for 5 days or more and radiographic evidence of acute rhinosinusitis.
Exclusion criteria
Exclusion criteria: (1) The patients should be treat with intravenous anitimicobial injection because of severe infectious disease (2) Purulent specimens are test agent- resistant bacteria. (3) The patients have improvements in clinical symptoms with another oral antibacterial agent before this examination. (4) The patients are suspected of recurent or odontogenic sinusitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary efficacy are determined by the patients with SNOT-16 (day 3-4). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) The efficacy are determined by otorhinolaryngologists with japanese scoring method for acute rhinosinusitis (day 3-4, 6-8, 13-15). 2) The efficacy are determined by the patients with SNOT-16 (day 6-8, 13-15) 3) The efficacy are evaluated by X ray and cultivation of bacteria (day 6-8) 4) The efficacy are evaluated by patients' diary | — |
Countries
Japan
Contacts
Public ContactTakayoshi Ueno
Hokuriku otolaryngology practiced expert study group Executive office
Outcome results
None listed