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Effect of ALDH2 polymorphism, gastric acid secretion level, and L-cystein administration on gastric acetaldehyde concentration

Effect of ALDH2 polymorphism, gastric acid secretion level, and L-cystein administration on gastric acetaldehyde concentration - Effect of ALDH2 polymorphism, gastric acid secretion level, and L-cystein administration on gastric acetaldehyde concentration

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000012378
Enrollment
20
Registered
2013-11-25
Start date
2013-01-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy volunterrs

Interventions

proton pump inhibito proton pump inhibito, L-cystein

Sponsors

Div. of Gastroenterology, Tohoku University Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: H. pylori-negative healthy male volunteers

Exclusion criteria

Exclusion criteria: ALDH2 dufficient subjects

Design outcomes

Primary

MeasureTime frame
Change of gastric acetaldehyde concentration among baseline, on PPI, and on PPI plus L-cystein

Countries

Japan

Contacts

Public ContactIijima Katsunori

Tohoku University Hospital Div. of Gastroenterology

kiijima@med.tohoku.ac.jp022-717-7171

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026