A phase II clinical trial of carbon-ion radiotherapy for patients with bone and soft tissue sarcomas not suited for surgical resection(HIMAT1341)

A phase II clinical trial of carbon-ion radiotherapy for patients with bone and soft tissue sarcomas not suited for surgical resection(HIMAT1341) - Carbon-ion radiotherapy for bone and soft tissue sarcomas (HIMAT1341)

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000012373

Enrollment

Registered

2013-12-01

Start date

2013-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bone and soft tissue sarcomas not suited for surgical resection

Interventions

Carbon-ion radiotherapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Histolocgically proven primary bone and soft tissue sarcomas 2) Unresectable tumor or patient's refusal of surgery 3) Not exceeding 15cm in tumor size 4) Measurable tumor 5) Age between 16 and 80 years old 6) PS 0-3 7) No distant metastasis 8) Expected to survival more than 6 months 9) Informed consent by patient

Exclusion criteria

Exclusion criteria: 1) Located in Head 2) Past history of irradiation to the target 3) Past history of chemotherapy within 2 weeks before treatment 4) Active double cancers 5) Uncontrolled infectious disease 6) Artifact affecting dose calculation 7) Other medical or psychological unsuitable reasons

Design outcomes

Primary

Measure	Time frame
two year local control rate	—

Secondary

Measure	Time frame
survival rate, progression free survival, complication rate	—

Countries

Japan

Contacts

Public ContactTerashima Kotaro

SAGA HIMAT Foundation Ion Bean Therapy Center

terashima-kotaro@saga-himat.jp0942-81-1897

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026