articular cartilage injury
Conditions
Interventions
injection of bone marrow mesenchymal cells into joint
no cells
Sponsors
Mukogawa Women's University
Osaka Univseristy, Hiroshima University, Osaka City Univeristy, Hyogo Medical University, Nara Medical University, Tomishiro Chuo Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) patients who are planning to receive bone marrow stimulation for articular cartilage defect 2) patients with more than 50% defects of articular cartilage (International Cartilage Repair Society articular cartilage injury classification grade 3 or 4 recognized by MRI) 3) patients with articular cartilage defect lager than 2cm2 recognized by MRI 4) patients with his or her consent by documents
Exclusion criteria
Exclusion criteria: 1) patients who underwent ACL and/or PCL reconstruction within 2 months 2) patients with active cancer 3) pregnant or possively pregnant patients, patients giving the breast to a child or expecting a child during the study periods 4) patients with infections (positive for anti-HIV antibody, HBs antigen, anti-HCV antibody or anti HTLV antibody 5) patients with a psychopathy 6) patients whom the researcher judged to be inappropriate to be enrolled in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| improvement of clinical symptoms | — |
Countries
Japan
Contacts
Public ContactShigeyuki Wakitani
Mukogawa Women's University School of Sports and HEalth Sciences
Outcome results
None listed