non small cell lung cancer
Conditions
Interventions
Nab-paclitaxel
Sponsors
Niigata Lung Cancer Treatment Group
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Non-small cell lung cancer proven by histology and/or cytology 2)EGFR mutation or ALK rearrangement status is not required 3)One or two prior cytotoxic chemotherapy 4)20 years or older 5)Performance Status 0-2 6)At least one or more measurable lesion by RECIST ver1.1 7)Adequate organ function 8)Life expectancy more than twelve weeks. 9)Written Informed Consent
Exclusion criteria
Exclusion criteria: 1)History of paclitaxel treatment 2)Severe complications 1:Type 2 DM treated with insulin injection 2:Symptomatic congestive heart failure or unstable angina or problematic arrhythmia or history of acute myocardial infarction within one year 3:Interstitial pneumonia or active radiation pneumonia or drug-induced pneumonia 3)Problematic infection 4)History of active double cancer 5)Severe drug allergy 6)No intention to birth control 7)Unstable psychic disorder 8)Decision of ineligibility by a physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety, Progression free survival, Disease control rate, Overall survival, Evaluation of sensory neuropathy using PNQ score | — |
Countries
Japan
Contacts
Public ContactSatoru Miura
Niigata University Medical & Dental Hospital Department of Medicine (II)
Outcome results
None listed