Non-small cell lung caner
Conditions
Interventions
Before and early after chemotherapy, both FDGPET/CT and 4DST PET/CT will be performed and compared to the clinical parameters. 4DSTPET/CT will be imaged 40min after injection, and FDGPET/CT 1hr after.
Sponsors
National Center for Global Health and Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients having pathological diagnosis of non-small cell lung cancer, of which stage 3B or 4, or recurrence after surgery. And of whom performance status is 0 or 1, and having enough good hematological and biochemical data tolerable for chemotherapy. And those who have signed the informed consent form.
Exclusion criteria
Exclusion criteria: Those who have not signed the informed consent form. Those who have symptomatic brain metastasis, or active double cancer, or active infectious disease, or spinal metastasis that required immediate surgery or radiotherapy, or uncontrollable hypertension, or ischemic heart disease, or uncontrollable diabetes. Those who have been decided not appropriate by the physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| If the tumor uptake reduction of 4DST after chemotherapy is larger and earlier than that of FDG or not. | — |
Secondary
| Measure | Time frame |
|---|---|
| The correlation of the tumor uptake reductions of 4DST or FDG after chemotherapy and the tumor volume reduction, and the progression free survival. | — |
Countries
Japan
Contacts
Public ContactRyogo Minamimoto
National Center for Global Health and Medicine Div.Nuclear Medicine, Dept.Radiology
Outcome results
None listed