The effect of tranexamic acid on blood loss in orthognathic surgery.

The effect of tranexamic acid on blood loss in orthognathic surgery. - The effect of tranexamic acid on blood loss in orthognathic surgery.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000012288

Enrollment

100

Registered

2013-11-13

Start date

2013-04-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Jaw deformities

Interventions

A loading dose of 10mg/kg of tranexamic acid is infused intravenously before surgery. A loading dose of 5ml of saline is infused intravenously before surgery.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients older than 16 years old and undergoing orthognathic surgery agreed to participate in this traial.

Exclusion criteria

Exclusion criteria: Exclusion criteria are atrial fibrillation,coronary artery disease treated with drug eluting stent,severe chronic renal failure,congenital or acquired thrombophilia,and known or suspected allergy to tranexamic acid.

Design outcomes

Primary

Measure	Time frame
intraoperative blood loss	—

Countries

Japan

Contacts

Public ContactAki Ito

Tokyo Metropolitan Ohtsuka Hospital Department of Stomatology

ot_koukuu@tmhp.jp03-3941-3211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026