Impact of corticosteroid on periarticular injection for pain control following total knee arthroplasty: a double-blind randomized trial

Impact of corticosteroid on periarticular injection for pain control following total knee arthroplasty: a double-blind randomized trial - Impact of corticosteroid on periarticular injection for pain control following total knee arthroplasty: a double-blind randomized trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000012257

Enrollment

Registered

2013-11-11

Start date

2013-11-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoarthritis, rheumatoid arthritis, avascular necrosis of femoral condyle

Interventions

A periarticular injection including methylprednisolone, ropivacaine, morphine, bosmin, and ketoprofen for pain after total knee arthroplasty A periarticular injection including ropivacaine, morphine,

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients scheduled for unilateral total knee arthroplasty

Exclusion criteria

Exclusion criteria: Patients scheduled for bilateral simultaneous total knee arthroplasty. Patients scheduled for unilateral total knee arthroplasty combined with implant removal. Patients who had allergy or intolerance to one of the study drugs, regular narcotic use, renal insufficiency and prolonged QT interval on ECG.

Design outcomes

Primary

Measure	Time frame
Visual Analogue Scale for postoperative pain at rest	—

Secondary

Measure	Time frame
Visual Analogue Scale for postoperative pain during activity Complication	—

Countries

Japan

Contacts

Public ContactSachiyuki Tsukada

Nekoyama Miyao Hospital Orthopaedic Surgery

s8058@nms.ac.jp025-282-2323

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026