ulcerative colitis, large bowel perforation, esophageal cancer, colorectal cancer
Conditions
Interventions
monocyte/neutrophil apheresis
non monocyte/neutrophil apheresis
Sponsors
Mie University Hospital
Department of Infectious Diseases, Hiroshima University Graduate School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Following patients at high risk for postoperative infection -wound class 2 and over -with infection -poor nutrition or general status -undergo major-invasive surgery
Exclusion criteria
Exclusion criteria: -patients with cardiovascular disease (acute myocardial infarction, ischemic heart disease, or arrhythmia requiring treatment within 6 months of onset) -with or with past histories of cerebral infarction or cerebrovascular disorder including intracerebral hemorrhage -patients with hypotension or systolic blood pressure of 80mmHg and under -pregnant or breast feeding women and women suspected of being pregnant -demented persons -patients with a histories of shock during extracorporeal circulation therapy -patients receiving angiotensin-converting enzyme inhibitors and inappropriate in these drugs withdrawal prior to apheresis -patients judged as inadequate for this study by attending physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation neutrophil function of patients at high risk for postoperative infection treated with monocyte/neutrophil apheresis | — |
Secondary
| Measure | Time frame |
|---|---|
| Identification of amount of blood apheresis needed for improvement in function of neutrophil | — |
Countries
Japan
Contacts
Public ContactToshimitsu Araki
Mie University Hospital Center of maternal and child health
Outcome results
None listed