Systemic sclerosis
Conditions
Sponsors
The University of Tokyo
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Patients with systemic sclerosis with sever skin sclerosis 2)Over 6 modified Rodnan total skin score with skin sclerosis on fingers, dorsal hands, forearms, and upper arms; change of total skin score is within 20% during the screening period (two months) 3)no malignancy 4)from 20 years old to 80 years old 5)Agreement to contraception during the study period 6)Patients who are able to give consent in writing after reading the explanatory text
Exclusion criteria
Exclusion criteria: 1)during treatment with equal drug 2)previous history of anaphylactic reactions to this drug 3)significant infection 4)significant liver damage 5)significant renal damage 6)pregnancy 7)breast-feeding 8)participating in other clinical trial within three months before the beginni ng of this trial 9)judged inappropriate for this study by the physicians
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sum of skin scores from 17 sites of the body (modified Rodnan total skin score) | — |
Countries
Japan
Contacts
Public ContactAyumi Yoshizaki
The University of Tokyo Department of Dermatology, Faculty of Medicine, Graduate School of Medicine
Outcome results
None listed