Suppressive effects of high-dose remifentanil on stress response of patients during cardiac surgery with cardiopulmonary bypass

Suppressive effects of high-dose remifentanil on stress response of patients during cardiac surgery with cardiopulmonary bypass - Suppressive effects of high-dose remifentanil on stress response of patients during cardiac surgery with cardiopulmonary bypass

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000012213

Enrollment

Registered

2013-11-05

Start date

2009-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients scheduled for elective cardiac surgery with CPB

Interventions

administer high dose remifentanil(1.0mcg/kg/min) during CPB administer low dose remifentanil(0.1mcg/kg/min) during CPB

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: primary cardiac surgery using CPB

Exclusion criteria

Exclusion criteria: LVEF<25% preoperative inotropic or intraaortic balloon pump support emergency surgery preoperative significant pulmonary, endocrine, metabolic, neurological disease

Design outcomes

Primary

Measure	Time frame
Stress hormone response (blood glucose, cortisol, ACTH, noradrenaline)	—

Countries

Japan

Contacts

Public ContactYuka Fujii

Kanazawa University Hospital Department of Anesthesiology

yfujii@staff.kanazawa-u.ac.jp0762652000

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026