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Clinical study of combination therapy of adoptive immunotherapy with proton therapy for pancreatic cancer

Clinical study of combination therapy of adoptive immunotherapy with proton therapy for pancreatic cancer - Clinical study of combination therapy of adoptive immunotherapy with proton therapy for pancreatic cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000012201
Enrollment
15
Registered
2013-11-01
Start date
2013-11-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pancreatic cancer

Interventions

Proton therapy Alpha-Beta T-cell Therapy

Sponsors

Hyogo Ion Beam Medical Center
Lead Sponsor
Seta Clinic Group
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1)Locally advanced pancreatic cancer eligible for the inclusion criteria and ineligible for the exclusion criteria of Hyogo Ion Beam Medical Center (2)Patients who can initiate immunotherapy within three months after proton therapy (3)over 20 years old (4)Performance Status is 0-2 (5)Survival more than three months (6)No serious abnormality in bone marrow, liver, and renal functions (7)Informed consent has been obtained

Exclusion criteria

Exclusion criteria: (1)Interstitial pneumonia (2)Active autoimmune disease (3)Active heart trouble (4)uncontrolable infectious diseases. (5)Serious drug allergy (6)Continuous systemic administration of steroids (7)Pregnancy (8)Positive for HIV or HTLV-1 (9)patients who are inadequate to enter this study due to the other reasons by physician's judgments

Design outcomes

Primary

MeasureTime frame
distant disease-free rate

Secondary

MeasureTime frame
overall survival survival rate local control rate frequency and type of adverse events QOL immunological parameters

Countries

Japan

Contacts

Public ContactKazuki Terashima

Hyogo Ion Beam Medical Center Department of Radiology

k.terashima@hibmc.shingu.hyogo.jp0791-58-0100

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026