Comparative analysis of the usefulness of endoscopic ultrasound guided fine needle aspiration (EUS-FNA) and mucosal incision assisted biopsy (MIAB) in the diagnosis of gastrointestinal stromal tumors (GIST) of the stomach.

Comparative analysis of the usefulness of endoscopic ultrasound guided fine needle aspiration (EUS-FNA) and mucosal incision assisted biopsy (MIAB) in the diagnosis of gastrointestinal stromal tumors (GIST) of the stomach. - Comparative analysis of the usefulness of EUS-FNA and MIAB in the diagnosis of GIST of the stomach.

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000012169

Enrollment

Registered

2013-11-05

Start date

2013-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastrointestinal stromal tumor

Interventions

EUS-FNA group: (1) Tissue sampling is performed for patients with suspected gastric GISTs by EUS-FNA. (2) When tissue samples obtained by EUS-FNA is sufficient for a differential diagnosis of Gastro

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) The patients who are suspected to have Gastric GIST by EUS (2) Tumor size ranges between 1 cm and 5 cm (3) Patients with tumors of extraluminal growth patterns are excluded. (4) The patients who personally give written informed consent to participate in this study.

Exclusion criteria

Exclusion criteria: (1) Patients who are not candidates for upper gastrointestinal endoscopy including ileus, gastrointestinal perforation, critical respiratory ailment, cardiovascular diseases, etc. (2) Patients taking antithrombotic treatment (3) Patients with bleeding tendency (4) Patients judged by the principal or sub-investigator to be unsuitable for the study (5) Patients without written informed consent

Design outcomes

Primary

Measure	Time frame
Comparison of successful tissue extraction rates of FNA and MIAB for pathological diagnosis of gastric GIST by H.E and immunohistochemistry staining.	—

Secondary

Measure	Time frame
(1) Comparison of the diagnostic yield of EUS-FNA and MIAB. (2) Comparison of safety of EUS-FNA and MIAB. (3) Comparison of procedure time and biopsy frequency of EUS-FNA and MIAB	—

Countries

Japan

Contacts

Public ContactTakashi Osoegawa

Graduate School of Medical Sciences, Kyushu University Department of Endoscopic Diagnostics and Therapeutics

t.osoegawa@gmail.com092-641-1151

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026