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Prospective study to investigate the performance of cytokine removal of polymethyl methacrylate hemofilters with two different membrane surface area

Prospective study to investigate the performance of cytokine removal of polymethyl methacrylate hemofilters with two different membrane surface area - Performance of cytokine removal of polymethyl methacrylate hemofilters with two different membrane surface area

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000012164
Enrollment
20
Registered
2013-10-30
Start date
2013-11-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe sepsis, Septic shock

Interventions

None listed

Sponsors

Department of Emergency and Critical Care Medicine, Chiba University, Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Svere sepsis/sptic shock patients with hypercytokinemia(IL-6 blood level is higher than 10000pg/mL) who recieve continuous hemodiafiltration using polymethylmethacrylate hemofilter

Exclusion criteria

Exclusion criteria: a) Patients who need to use smaller hemofiter (mambrane surface area:0.3m2 or 0.6m2) b) under 15 years old c) Pregnant woman d) Patients whom doctors judge as out of the adaptation

Design outcomes

Primary

MeasureTime frame
Cytokine clearance of hemofilters, and duration those keep the clearance

Countries

Japan

Contacts

Public ContactNoriyuki Hattori

Chiba University, Graduate School of Medicine Department of Emergency and Critical Care Medicine

hat@shogo.com043-222-7171

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026