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local intraarterial fibrinolysis in central retinal arteryy occlusion

local intraarterial fibrinolysis in central retinal arteryy occlusion - LIF in CRAO

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000012161
Enrollment
30
Registered
2013-10-30
Start date
2013-10-29
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

central retinal artery occlusion

Interventions

local intraarterial fibrinosys using urokinase

Sponsors

St. Marianna University School of Medicine, Yokohama City Seibu Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1)Aged 18 and over 2)Within 15 hours after development of symptoms 3)Visual acuity is 20/400 or loss 4)The case in which visual acuity improvement is not obtained under medical treatment (eye massage) conventionally which was performed by the time it resulted in endovascular treatment 5)The case which accepts the occlusion of clear CRA in fundus examination

Exclusion criteria

Exclusion criteria: 1)improvement of visual acuity before treatment 2)the case in which the difficulty is became clear by examination before treatment for the approach to an ophthalmic artery 3)the case in which cerebral hemorrhage is diagnosed by examination before treatment 4)When a systemic bleeding disorder exists within three months 5)When consent acquisition for treatment cannot be carried out 6)The case diagnosed as angitis clinically or on examination 7)When the phenomenon remarkably being difficultty for treatment exists

Design outcomes

Primary

MeasureTime frame
1. improvement of vision 48 hours after the treatment 2. improvement of vision 2 weeks after the treatment

Secondary

MeasureTime frame
1. improvement of angiographic visualization of optic artery after treatment 2. improvement of fundus examination after treatment 3. complication

Countries

Japan

Contacts

Public Contactatsushi tsuchiya

St. Marianna University School of Medicine, Yokohama City Seibu Hospital neurology

a-t1@marianna-u.ac.jp045-366-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026