Gastric Cancer
Conditions
Interventions
Prophylactic antibacterial drug only for the operative day
Prophylactic antibacterial drug until the 7th postoperative day
Sponsors
Shizuoka Cancer Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Biopsy specimen from the primary lesion shows adenocarcinoma 2) R0 resection or R1 resection with CY1 by gastrectomy with D2 lymph node dissection 3) The maximum value of drain amylase concentration is above 3000 (IU/L) 4) Esophageal invasion is less than 3cm. 5) Eeatern clinical oncology group performans status is 0 or 1 6) No previous chemotherapy or radiation including those for other cancers 7) Fulfil all following conditions WBC > 3,000/mm3 Plt > 100,000/mm3 AST < 100 IU/L ALT < 100IU/L T.Bil < 2.0 g/dl Cre < 1.5mg/dl 8) written informed consent
Exclusion criteria
Exclusion criteria: 1) Having other active infectious disease 2) combined resection (gall bladder and spleen are exceptions) 3) Possibly pregnant, or breast feeding woman 4) with psychiatric disorder 5) Receiving steroids 6) With Acute myocardial infaction in 6 months or with unstable ungina 7) With uncontrolled hypertention 8) With uncontrolled diabetes mellitus 9) With pulmonary disease and require continuous oxygen therapy 10) With allergy to cephalosporin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of post-operative intra-abdominal infectious complications (anastomotic leakage, pancreas related infection, and intra-abdominal abscess) | — |
Countries
Japan
Contacts
Public ContactYuichiro Miki
Shizuoka Cancer Center Gastric Surgery
Outcome results
None listed