gastroesophageal reflux disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: A diagnosis of erosive GERD including gradeM was made by the endoscopic examination before the PPI dosage start. The patient who takes a rabeprazole sodium 10mg in the morning after the diagnose of GERD. Patient having less than 95% of % SLEEP by actigraph.
Exclusion criteria
Exclusion criteria: They were pregnant or nursing mother, or used atazanavir sulfate, or had allergy to rabeprazole sodium, Zollinger-Ellison syndrome and peptic ulcer disease. Disease-related exclusion criteria included the following: severe disease of any major body system; malignant disease of any kind; gastrointestinal diseases such as esophageal stricture, primary esophagus motor disorders, systemic sclerosis, severe sleep disorder, depression or any other psychiatric disease associated with worsened QOL, past history of upper gastrointestinal surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| parameters by actigraph | — |
Countries
Japan
Contacts
Osaka City University Graduate School of Medicine Osaka City University Graduate School of Medicine