Prostate cancer
Conditions
Interventions
Hypo-fractionated stereotactic intensity-modulated radiotherapy (54Gy/15 fractions/3 weeks) is applied after 4 to 8 months neoadjubant hormonal (CAB) therapy.
Sponsors
Department of Radiation Oncology & Image-applied Therapy, Kyoto University Graduate School of Medicine
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) Histo-pathologically confirmed as adenocarcinoma of the prostate. 2) Prostate cancer cases classified to low-risk or intermediate-risk based on the D'Amico's definition. 3) Age at the registration is >=50 and <80 years old. 4) Performance status is 0 or 1 with Cooperative Oncology Group definition. 5) Cases submitted a written informed consent.
Exclusion criteria
Exclusion criteria: 1) Active double cancer 2) Uncontrolled diabetes mellitus (HbA1c>+8.4%) 3) Severe coexisting diseases such as collagen disease, heart disease, respiratory disease and liver disease. 4) Psychotic disease 5) History of pelvic irradiation 6) History of pelvic surgery except for appendectomy and femoral herniation. 7) Surgical managements to the prostate 8) Chemotherapy to the prostate cancer 9) Inflammatory bowel diseases 10) Cases who are difficult to discontinue the administration of anticoagulant drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidences of acute adverse events | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidences of late adverse events at 2 years PSA recurrence-free suravival rate at 2 years | — |
Countries
Japan
Contacts
Public ContactTakashi Mizowaki
Kyoto University Graduate School of Medicine Department of Radiotherapy
Outcome results
None listed